believe to be the first such case , a valet sticking to his preventative HIV medication has become infected with the computer virus . While this highlight the motivation to not become self-satisfied in the aspect of positive trial data , the tenuity of such an instance still back the use of these drugs .
Announcedat the 2016 Conference on Retroviruses and Opportunistic Infections , the person , a 43 - year - old sunny man who had sex with other men , tested positive for HIV despite taking pre - exposure prophylaxis ( PrEP ) drugs successfully for one yr .
Called Truvada , thePrEPpill is a cocktail of two different antiviral drug that has been under scrutiny for several years now as a potential preventative measure for mellow - risk group , such as mirthful men or injecting drug substance abuser . The mind is that by keeping a high enough level of anti - HIV drug in the system , the computer virus is ineffective to gain a foothold upon entering a susceptible individual , thus representing a barrier to contagion .
And test have been exceedingly encouraging , withstudiessuggesting that high adherence – assume the pill 4 to 7 prison term a hebdomad – can offerclose to 100 per centum protective cover . Though as would be expected , with reduced bond come reduced efficacy . But that is where this present face study is surprising – the man had been come after his regimen nearly .
Not only did his prescription medicine records show that he had been collecting his medication , but blood tests observe his diagnosis show that he had consistently been taking Truvada in the preceding 1 to 2 months . By await for the appearance of antibodies against HIV in his blood , the researchers concluded that this timeframe overlapped with the estimate point that he became septic .
After conducting further analysis of the virus circulating in his system of rules , a low amount of genetic diversity indicated that the seed of transmission was a exclusive source , rather than multiple individuals . Critically , it was found that the computer virus was resistant to several different antiviral drug , comprise the most probable account for the medication ’s nonstarter to protect from transmission . With a grasp of drugs available to tackle HIV , the man is respond to other therapy that his virus has not establish resistance to , Poz report .
While clearly effectual , this serves as a harsh reminder that taking preparation does not make you dense . It may offer some slack , but rubber are still a proved method acting that not only protect against HIV , but other STIs too .
